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Epidemiologist

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"When I discovered epidemiology I thought I had died and gone to heaven," says Linda Cowan. She is an epidemiologist and a professor at the University of Oklahoma.

She loves to solve mysteries, collect evidence and study biology. She does all these things as an epidemiologist. When she first started her career over 30 years ago, she dreamed of making an important discovery about what causes disease. She has realized just how difficult it is to make such a breakthrough.

"Prevention is always the goal, so any steps in that direction is a reward," she says.

These days she is rewarded by preparing students for the field and moving the research forward. She says the field is very exciting because it offers many opportunities for international work and travel. She has done a lot of work in Africa.

Cowan and her colleague Helene Carabin have a pilot study in Burkina Faso, a landlocked country in western Africa. It is one of the poorest countries in the world. They are studying epilepsy and a parasitic disease called neurocysticercosis that can cause epilepsy.

Due to issues involving poverty, hygiene, food preparation and sanitation, the human brain may become infected with the larval worm of this parasitic disease. This can cause seizures and epilepsy.

"People with epilepsy are marginalized, cannot marry and are thought to be contagious. So when one has a fit, they are left alone and people run away," says Carabin. She is also an epidemiologist and a professor at the University of Oklahoma.

Carabin and Cowan visited an isolated village west of the capital city Ouagadougou. They met with a nurse and found that no one with epilepsy was being treated.

The local team of researchers interviewed people and sent those with epilepsy to a CT scanner to get images of their brains. The researchers were looking for people with worm larvae in their brains. They found that 50 percent of people with epilepsy in that part of the world indeed have the larvae in their brains.

"But the most inspiring result was that, when I went back to the village last January to thank the villagers for their participation, we were told by the nurse that he was now treating 30 people for epilepsy! The chief of the village also mentioned during the meeting (which took place at the village center under a mango tree) that people with epilepsy should go to the nurse and get treated because the 'modern' treatment (in contrast to treatment provided by traditional healers) does work.

"So it seems that simply talking about the issue improved the health of at least 30 people in that village. These are the sorts of experiences that make us happy. We hope to continue this research by testing an intervention to reduce the infection with the worm and ultimately prevent several cases of epilepsy in that region," says Carabin.

The logic behind designing a study is Carabin's favorite part of the job. Like Cowan, she also likes to solve mysteries.

"You have a disease (or infection) that will happen in some people and not in others. Why? I am a veterinarian by training and decided to become an epidemiologist because I hated treating animals without knowing what had caused the disease. Prevention is so much more rewarding, in my view, anyway. And in order to prevent, you need to know the causes."

Getting funding for research is the greatest challenge for epidemiologists, says Carabin.

Cowan agrees that a lot of good project ideas go unfunded. The studies are expensive. For example, a lot of workers are required to follow 1,000 research subjects for years, and collect and analyze their medical data, which can be costly.

Colin L. Soskolne specializes in environmental epidemiology. He graduated in applied mathematics and computer science. Then he worked as a biostatistician for seven years. Next he earned his PhD in epidemiology.

"I like the fact that my research can influence public policy at the highest levels. This impact makes what I do seem all the more important for keeping communities healthy," he says.

As with most health researchers, Soskolne's workday is typically longer than eight hours. He is usually in his office whittling down a long list of responsibilities. The list includes writing papers on completed research, sending research reports to agencies, filling in grant applications for new research that he would like to see undertaken, preparing lectures and helping students.

"All in all, the days are exciting and challenging. I like to work long hours because the work of the epidemiologist is so important," says Soskolne.

He says anyone with an analytical mind who is determined to work in public health could be an epidemiologist.

"Physical and also personality peculiarities will define the scope of the job best suited to the individual. For instance, not all epidemiologists are good (or needed) in public speaking. Some people are best placed to work behind the scenes. Others do well being in the trenches. Both are needed," says Soskolne.

He explains that some epidemiologists specialize in infectious diseases. This type of disease is caused by bugs of some sort. Other epidemiologists focus on diseases that take a longer time to develop. This specialization might focus on exposure to pollution, or diseases caused by lifestyle choices such as smoking.

"The challenge often is to disentangle genetic from environmental causes of disease. Whether one works, for instance, in universities doing research and teaching, or in public health units responding to disease emergencies and health inspection monitoring services, the aim is always to prevent disease or injuries from occurring," says Soskolne.

He says the maxim of epidemiologists is "an ounce of prevention is worth a pound of cure."

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